Supplying the Cells to Improve the Human Condition

iOrganBio's CellForge™ Platform transforms the way we create human cells—enabling reproducible, scalable, and intelligent cell manufacturing for in vivo modeling and cell therapies.

WE ARE ENTERING THE AGE OF
PROGRAMMABLE BIOLOGY.

IORGANBIO's proprietary CellForge™ platform brings engineering precision to the complexity of cellular biology.

◆Powered by advanced AI algorithms, CellForge integrates the genetic background and molecular state of both starting and target cell populations to dynamically tailor cell culture conditions and differentiation protocols.

◆Cell manufacturing is performed in an AI-guided 3D incubator system allowing quasi-continuous transcriptomics readouts, enabling real-time feedback and automated process optimization.

◆This closed-loop system provides adaptive control throughout the differentiation process, ensuring unprecedented reproducibility, scalability, and predictability in generating highly specialized cell types, tissues, and organoids.

CellForge Digitizes the Development and Manufacturing of Human Cells

A first-of-its-kind platform that merges AI prediction, biological sensing, and automated 3D incubation — turning complex cellular science into a programmable process.

STEP 1

Define target cells

Select from IORGANBIO's in vivo Functional Human Cell Atlas
Provide cells or cell characteristics

STEP 2

Characterize biological state of starting cells

Genomics
Transcriptomics
Proteomics

STEP 3

AI-agent guides differentiation towards target cell state

Continuous feedback loop
Fully automated 3D incubators

STEP 4

Delivery of cell product to partner specification

Full process data and endpoint package demonstrating match to target profile

What Makes iOrganBio Unique

No more black box biology. No more waiting 6 months for cell access. This is programmable cell manufacturing.

Digitally Defined Cell Profile

Every batch meets a fully defined biological profile

Reproducible

Every batch meets the desired profile

Scalable

iOB can deliver desired cells at unprecedented volume

Generalizable

CellForge can access any cell or organoid type

Adaptable

CellForge can use any cells as input

Meet our
Founding Team

A multidisciplinary team of engineers, scientists, and entrepreneurs leading the next chapter of biotechnology.

Dr. Daniel Delubac

Chief Executive

Prof. Shuibing Chen

Chief Scientist

Prof. Xiling Shen

Chief Technologist

OUR INVESTORS AND PARTNERS

Backed by Pivotal Scientific Research

Our scientific team is actively publishing the science behind CellForge in top journals and conferences.

A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages

Cell Stem Cell, September 2017

A human pluripotent stem cell–based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids

Cell Stem Cell, July 2020

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids

Nature, August 2020

An Immuno-cardiac Model for macrophage-mediated inflammation

Circulation research, 2021

Human vascularized macrophage–islet organoids

Cell Stem Cell, November 2024

Let us supply the exact cells you need

We are bringing engineering precision to the complexity of cellular biology

Built to Cure.
Designed for Collaboration.

Whether you're pioneering new treatments, advancing diagnostics, or investing in the next biotech platform — Let's Build the Future of Cell Therapies Together

Partner With Us